I agree that the eyes and lips look extremely odd. I'm hoping it was a bad case of photoshop, because, if not, this otherwise beautiful young lady took some very ill-advised surgery. She would be attractive, but the oversizing kills it for me.
I don't even think it was surgery (extending the width of the mouth would be quite a painful thing - think about it xD). It could be either overdone photoshop as you suggested or if you put lipstick beyond the actual lips, they also look a lot bigger . Nice pic - apart from the slightly oversized mouth !